恩杂鲁胺;恩扎鲁胺 Enzalutamide
交易须知
enzalutamide产品活性：enzalutamide (mdv3100) 是一种雄激素受体 (androgen receptor (ar)) 拮抗剂，在lncap前列腺细胞中抑制ar 的 ic50 值为36 nm。
研究领域：others | autophagy
作用靶点：androgen receptor | autophagy
in vitro: enzalutamide has greater affinity to ar than bicalutamide does in a competition assay with 16β-[18f]fluoro-5α-dht (18-fdht) in castration-resistant lncap/ar cells (ar-overexpressing). while enzalutamide shows no agonism in lncap/ar prostate cells. enzalutamide antagonizes induction of prostate-specific antigen (psa) and transmembrane serine protease 2 (tmprss2), combination with the synthetic androgen r1881 in parental lncap cells. enzalutamide inhibits the transcriptional activity of a mutant ar protein (w741c, mutation of trp741 to cys). enzalutamide also prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.
in vivo: enzalutamide induces great tumor regression in castrate male mice bearing lncap/ar xenografts at a dose of 10 mg/kg. enzalutamide shows dose-independent pharmacokinetics at intravenous and oral doses of 0.5-5 mg/kg.
相关产品：fda-approved drug library plus | drug repurposing compound library | fda-approved drug library mini | fda-approved drug library | anti-cancer compound library | drug repurposing compound library plus | bioactive compound library plus | autophagy compound library | apalutamide | dhea | bicalutamide | dimethylcurcumin | flutamide | darolutamide | danazol | spironolactone | rad140 | azd3514 | bms-564929 | 3,3'-diindolylmethane | n-desmethyl enzalutamide | cyproterone acetate | d4-abiraterone | glpg0492 | lgd-3303 | boldenone undecylenate | ut-155 | andarine | lupeol | ostarine | ailanthone | ly2452473 | mk-0773 | orm-15341 | acp-105 | epiandrosterone | gsk-2881078 | lgd-4033
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恩杂鲁胺;恩扎鲁胺 Enzalutamide
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enzalutamide产品活性：enzalutamide (mdv3100) 是一种雄激素受体 (androgen receptor (ar)) 拮抗剂，在lncap前列腺细胞中抑制ar 的 ic50 值为36 nm。
研究领域：others | autophagy
作用靶点：androgen receptor | autophagy
in vitro: enzalutamide has greater affinity to ar than bicalutamide does in a competition assay with 16β-[18f]fluoro-5α-dht (18-fdht) in castration-resistant lncap/ar cells (ar-overexpressing). while enzalutamide shows no agonism in lncap/ar prostate cells. enzalutamide antagonizes induction of prostate-specific antigen (psa) and transmembrane serine protease 2 (tmprss2), combination with the synthetic androgen r1881 in parental lncap cells. enzalutamide inhibits the transcriptional activity of a mutant ar protein (w741c, mutation of trp741 to cys). enzalutamide also prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.
in vivo: enzalutamide induces great tumor regression in castrate male mice bearing lncap/ar xenografts at a dose of 10 mg/kg. enzalutamide shows dose-independent pharmacokinetics at intravenous and oral doses of 0.5-5 mg/kg.
相关产品：fda-approved drug library plus | drug repurposing compound library | fda-approved drug library mini | fda-approved drug library | anti-cancer compound library | drug repurposing compound library plus | bioactive compound library plus | autophagy compound library | apalutamide | dhea | bicalutamide | dimethylcurcumin | flutamide | darolutamide | danazol | spironolactone | rad140 | azd3514 | bms-564929 | 3,3'-diindolylmethane | n-desmethyl enzalutamide | cyproterone acetate | d4-abiraterone | glpg0492 | lgd-3303 | boldenone undecylenate | ut-155 | andarine | lupeol | ostarine | ailanthone | ly2452473 | mk-0773 | orm-15341 | acp-105 | epiandrosterone | gsk-2881078 | lgd-4033
MedChemExpress LLC
郑先生
86-021-58955995
17321200539
久洲地板 地板保养的窍门和注意事项
瑞余烤鱼堂投资，为创业者带来更多的市场
猪场的疫病监测与猪群免疫监测
地上行走的珍品，仔细想了想，养驴其实真的赚钱
代办日本签证 | 日本签证办理资讯
恩杂鲁胺;恩扎鲁胺 Enzalutamide
周口市鹿邑县简约天花板多人采购表示满意
河北浙江阿迪达斯童装厂家-有信誉度的浙江阿迪达斯童装厂家当属峰运动
营口彩钢瓦撕碎机型号河南诺德制造
研磨时光咖啡加盟条件有哪些?加盟具有哪些优势?
屯溪当地哪家公司代做可行做的好
班尔奇全屋定制加盟费用及利润分析
浙江美容主诊医师挂靠价格 医疗美容人才网专注医疗美容行业
先迪户外钓箱钓椅之标准型钓箱椅
推进大水面生态渔业发展领导小组赴江西调研大水面渔业
黄焖鸡米饭一年赚多少秦孝公品牌快餐加盟黄焖鸡
蔬菜脱水烘干流水线 食用菌烘干设备 价格便宜
牛小嫩串串香加盟怎么样
离心风机箱的特性
平膜压力变送器、齐平膜型压力传感器、卫生型压力传感器